Chemokine (C-C Motif) Ligand 21 (CCL21) (Middle Region) Peptide
CCL21
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CCL21 products
- CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ADPKELWVQQ LMQHLDKTPS PQKPAQGCRK DRGASKTGKK GKGSKGCKRT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- CCL21 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))
- Background
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This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
Alias Symbols: ECL, SLC, CKb9, TCA4, 6Ckine, SCYA21
Protein Size: 134 - Gene ID
- 6366
- NCBI Accession
- NM_002989, NP_002980
- UniProt
- O00585
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