APOBEC1 Complementation Factor (A1CF) (N-Term) Peptide
A1CF
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511770
Quick Overview for APOBEC1 Complementation Factor (A1CF) (N-Term) Peptide (ABIN5511770)
Target
A1CF
(APOBEC1 Complementation Factor (A1CF))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- LGTCPEPEAS MSTAIPGLKK GNNALQSIIL QTLLEKENGQ RKYGGPPPGW
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-A1CF Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- A1CF (APOBEC1 Complementation Factor (A1CF))
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Background
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Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.
Protein Size: 659 -
Gene ID
- 29974
Target
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