D-Amino-Acid Oxidase (DAO) (Middle Region) Peptide
DAO
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all D Amino Acid Oxidase (DAO) products
- D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VAAGLWQPYL SDPNNPQEAD WSQQTFDYLL SHVHSPNAEN LGLFLISGYN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- DAO Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))
- Background
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This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known, it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
Alias Symbols: DAAO, OXDA, DAMOX
Protein Size: 347 - Gene ID
- 1610
- NCBI Accession
- NM_001917, NP_001908
- UniProt
- P14920
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