D-Amino-Acid Oxidase (DAO) (Middle Region) Peptide
DAO
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511833
Quick Overview for D-Amino-Acid Oxidase (DAO) (Middle Region) Peptide (ABIN5511833)
Target
D Amino Acid Oxidase (DAO)
(D-Amino-Acid Oxidase (DAO))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- VAAGLWQPYL SDPNNPQEAD WSQQTFDYLL SHVHSPNAEN LGLFLISGYN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- DAO Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))
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Background
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This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known, it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
Alias Symbols: DAAO, OXDA, DAMOX
Protein Size: 347 -
Gene ID
- 1610
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NCBI Accession
- NM_001917, NP_001908
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UniProt
- P14920
Target
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