Anoctamin 1, Calcium Activated Chloride Channel (ANO1) (C-Term) Peptide
ANO1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512016
Quick Overview for Anoctamin 1, Calcium Activated Chloride Channel (ANO1) (C-Term) Peptide (ABIN5512016)
Target
ANO1
(Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LMVELFMREE QDKQQLLETW MEKERQKDEP PCNHHNTKAC PDSLGSPAPS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ANO1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
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Background
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ANO1 is a calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. It is required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. It acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Alias Symbols: ANO1,DOG1,ORAOV2,TAOS2,TMEM16A,
Protein Size: 986 -
Gene ID
- 55107
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NCBI Accession
- NP_060513
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UniProt
- Q5XXA6
Target
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