Aminolevulinate Dehydratase (ALAD) (Middle Region) Peptide
ALAD
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512124
Quick Overview for Aminolevulinate Dehydratase (ALAD) (Middle Region) Peptide (ABIN5512124)
Target
ALAD
(Aminolevulinate Dehydratase (ALAD))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- VPSRVPKDER GSAADSEESP AIEAIHLLRK TFPNLLVACD VCLCPYTSHG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ALAD Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ALAD (Aminolevulinate Dehydratase (ALAD))
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Background
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The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 Molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Alias Symbols: PBGS, ALADH
Protein Size: 330 -
Gene ID
- 210
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NCBI Accession
- NM_000031, NP_000022
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UniProt
- P13716
Target
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