Aldolase B, Fructose-Bisphosphate (ALDOB) (N-Term) Peptide
ALDOB
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ALDOB products
- ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ADESVGTMGN RLQRIKVENT EENRRQFREI LFSVDSSINQ SIGGVILFHE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ALDOB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
- Background
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Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
Alias Symbols: ALDOB,ALDB,
Protein Size: 364 - Gene ID
- 229
- NCBI Accession
- NP_000026
- UniProt
- P05062
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