STE20-Related Kinase Adaptor beta (STRADB) (Middle Region) Peptide
STRADB
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512129
$160.46
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100 μg
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Quick Overview for STE20-Related Kinase Adaptor beta (STRADB) (Middle Region) Peptide (ABIN5512129)
Target
STRADB
(STE20-Related Kinase Adaptor beta (STRADB))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- RLHTPSSKTF SPAFFSLVQL CLQQDPEKRP SASSLLSHVF FKQMKEESQD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- STRADB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- STRADB (STE20-Related Kinase Adaptor beta (STRADB))
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Background
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This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PAPK, ILPIP, ILPIPA, ALS2CR2, CALS-21, PRO1038
Protein Size: 418 -
Gene ID
- 55437
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NCBI Accession
- NM_001206864, NP_001193793
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UniProt
- Q9C0K7
Target
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