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T-Complex 1 (TCP1) (C-Term) Peptide

TCP1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5512203

Quick Overview for T-Complex 1 (TCP1) (C-Term) Peptide (ABIN5512203)

Target

TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Origin

Human

Source

  • 9
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    KQAGVFEPTI VKVKSLKFAT EAAITILRID DLIKLHPESK DDKHGSYEDA

    Characteristics

    This is a synthetic peptide designed for use in combination with anti- TCP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

    Background

    The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.

    Alias Symbols: CCT1, CCTa, D6S230E, CCT-alpha, TCP-1-alpha

    Protein Size: 556

    Gene ID

    6950

    NCBI Accession

    NM_030752, NP_110379

    UniProt

    P17987
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