Ubiquitin-Conjugating Enzyme E2C (UBE2C) (Middle Region) Peptide
UBE2C
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all UBE2C products
- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SAFPESDNLF KWVGTIHGAA GTAVGSIRTS STVCLLSGPR ETQDSSKPLV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-UBE2C Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
- Background
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.
Alias Symbols: UBCH10, dJ447F3.2
Protein Size: 161 - Gene ID
- 11065
- NCBI Accession
- NM_001281741, NP_861515
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