TNF Receptor-Associated Factor 3 (TRAF3) (C-Term) Peptide
TRAF3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512371
$160.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
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Quick Overview for TNF Receptor-Associated Factor 3 (TRAF3) (C-Term) Peptide (ABIN5512371)
Target
TRAF3
(TNF Receptor-Associated Factor 3 (TRAF3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- SRRHLGDAFK PDPNSSSFKK PTGEMNIASG CPVFVAQTVL ENGTYIKDDT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRAF3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))
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Background
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The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.
Alias Symbols: TRAF3,CAP1, CRAF1,
Protein Size: 485 -
Gene ID
- 7187
Target
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