IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3) (Middle Region) Peptide
IKZF3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512380
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3) (Middle Region) Peptide (ABIN5512380)
Target
IKZF3
(IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- YACQRRDALT GHLRTHSVEK PYKCEFCGRS YKQRSSLEEH KERCRTFLQS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-IKZF3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
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Background
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IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
Protein Size: 263 -
Gene ID
- 22806
Target
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