Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (N-Term) Peptide
MAP2K7
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512416
Quick Overview for Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (N-Term) Peptide (ABIN5512416)
Target
MAP2K7
(Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- LNLDISPQRP RPTLQLPLAN DGGSRSPSSE SSPQHPTPPA RPRHMLGLPS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- MAP2K7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
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Background
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The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.
Alias Symbols: MEK, MKK7, JNKK2, MEK 7, MAPKK7, PRKMK7, SAPKK4, SAPKK-4
Protein Size: 462 -
Gene ID
- 5609
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NCBI Accession
- NM_001297555, NP_660186
Target
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