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C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (N-Term) Peptide

MERTK Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5512419

Quick Overview for C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (N-Term) Peptide (ABIN5512419)

Target

MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Origin

Human

Source

  • 12
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequence

    PEPVNIFWVQ NSSRVNEQPE KSPSVLTVPG LTEMAVFSCE AHNDKGLTVS

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-MERTK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

    Background

    This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

    Alias Symbols: MERTK,MER,

    Protein Size: 999

    Gene ID

    10461

    NCBI Accession

    NP_006334

    UniProt

    Q12866
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