C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (N-Term) Peptide
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- Target See all MERTK products
- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PEPVNIFWVQ NSSRVNEQPE KSPSVLTVPG LTEMAVFSCE AHNDKGLTVS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MERTK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
- Background
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This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
Alias Symbols: MERTK,MER,
Protein Size: 999 - Gene ID
- 10461
- NCBI Accession
- NP_006334
- UniProt
- Q12866
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