Nonhomologous End-Joining Factor 1 (NHEJ1) (Middle Region) Peptide
NHEJ1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512427
Quick Overview for Nonhomologous End-Joining Factor 1 (NHEJ1) (Middle Region) Peptide (ABIN5512427)
Target
NHEJ1
(Nonhomologous End-Joining Factor 1 (NHEJ1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- ENSLLAKVFI TKQGYALLVS DLQQVWHEQV DTSVVSQRAK ELNKRLTAPP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- NHEJ1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))
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Background
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Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
Alias Symbols: XLF
Protein Size: 299 -
Gene ID
- 79840
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NCBI Accession
- NM_024782, NP_079058
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UniProt
- Q9H9Q4
Target
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