Trinucleotide Repeat Containing 6B (TNRC6B) (Middle Region) Peptide
Quick Overview for Trinucleotide Repeat Containing 6B (TNRC6B) (Middle Region) Peptide (ABIN5512561)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- STEWKDPKNT GGWNDYKNNN SSNWGGGRPD EKTPSSWNEN PSKDQGWGGG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- TNRC6B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TNRC6B (Trinucleotide Repeat Containing 6B (TNRC6B))
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Background
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Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.
Protein Size: 1029 -
Gene ID
- 23112
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NCBI Accession
- NM_001024843, NP_001020014
Target
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