Glutathione Peroxidase 1 (GPX1) (Middle Region) Peptide
GPX1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Glutathione Peroxidase 1 (GPX1) products
- Glutathione Peroxidase 1 (GPX1)
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DPKLITWSPV CRNDVAWNFE KFLVGPDGVP LRRYSRRFQT IDIEPDIEAL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GPX1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Glutathione Peroxidase 1 (GPX1)
- Background
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This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: GPXD, GSHPX1
Protein Size: 202 - Gene ID
- 2876
- NCBI Accession
- NP_000572
- UniProt
- A0A087WUQ6
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