NLR Family, Pyrin Domain Containing 12 (NLRP12) (N-Term) Peptide
NLRP12
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NLRP12 products
- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LEVSLVTPRK DPQETYRDYV RRKFRLMEDR NARLGECVNL SHRYTRLLLV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NLRP12 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
- Background
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This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.
Alias Symbols: NLRP12,NALP12,PYPAF7,RNO,
Protein Size: 1061 - Gene ID
- 91662
- NCBI Accession
- NP_653288
- UniProt
- P59046
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