Centriole, Cilia and Spindle Associated Protein (CCSAP) (Middle Region) Peptide
CCSAP
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CCSAP products
- CCSAP (Centriole, Cilia and Spindle Associated Protein (CCSAP))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KDVEDKPEQQ TRTRETDKSP TSTEPRQQPS ALFARGNRKA VKSPQRSSSK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- C1ORF96 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CCSAP (Centriole, Cilia and Spindle Associated Protein (CCSAP))
- Synonyms
- C1orf96 Peptide, CSAP Peptide, 1700054N08Rik Peptide, AI853424 Peptide, centriole, cilia and spindle associated protein Peptide, CCSAP Peptide, Ccsap Peptide
- Background
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Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle. May play a role in embryonic development. May be required for proper cilia beating.
Alias Symbols: CSAP, C1orf96
Protein Size: 270 - Gene ID
- 126731
- NCBI Accession
- NM_145257, NP_660300
- UniProt
- Q6IQ19
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