Centriole, Cilia and Spindle Associated Protein (CCSAP) (Middle Region) Peptide
CCSAP
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512666
$160.46
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100 μg
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Quick Overview for Centriole, Cilia and Spindle Associated Protein (CCSAP) (Middle Region) Peptide (ABIN5512666)
Target
CCSAP
(Centriole, Cilia and Spindle Associated Protein (CCSAP))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- KDVEDKPEQQ TRTRETDKSP TSTEPRQQPS ALFARGNRKA VKSPQRSSSK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- C1ORF96 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CCSAP (Centriole, Cilia and Spindle Associated Protein (CCSAP))
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Background
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Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle. May play a role in embryonic development. May be required for proper cilia beating.
Alias Symbols: CSAP, C1orf96
Protein Size: 270 -
Gene ID
- 126731
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NCBI Accession
- NM_145257, NP_660300
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UniProt
- Q6IQ19
Target
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