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Natriuretic Peptide A (NPPA) (Middle Region) Peptide

NPPA Reactivity: Human Host: Synthetic WB, BP
Catalog No. ABIN5512752

Quick Overview for Natriuretic Peptide A (NPPA) (Middle Region) Peptide (ABIN5512752)

Target

NPPA (Natriuretic Peptide A (NPPA))

Origin

Human

Source

  • 6
Synthetic

Application

Western Blotting (WB), Blocking Peptide (BP)
  • Protein Region

    Middle Region

    Sequence

    EVSPAQRDGG ALGRGPWDSS DRSALLKSKL RALLTAPRSL RRSSCFGGRM

    Characteristics

    This is a synthetic peptide designed for use in combination with anti- PRKACA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    NPPA (Natriuretic Peptide A (NPPA))

    Background

    The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1.

    Alias Symbols: ANF, ANP, CDD, CDP, PND, ATFB6, ATRST2, CDD-ANF

    Protein Size: 153

    Gene ID

    4878

    NCBI Accession

    NM_006172, NP_006163

    UniProt

    P01160
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