Colony Stimulating Factor 1 Receptor (CSF1R) (Middle Region) Peptide
CSF1R
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512789
Quick Overview for Colony Stimulating Factor 1 Receptor (CSF1R) (Middle Region) Peptide (ABIN5512789)
Target
CSF1R
(Colony Stimulating Factor 1 Receptor (CSF1R))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- DPTQLPYNEK WEFPRNNLQF GKTLGAGAFG KVVEATAFGL GKEDAVLKVA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CSF1R Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
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Background
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The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants.
Alias Symbols: FMS, CSFR, FIM2, HDLS, C-FMS, CD115, CSF-1R, M-CSF-R
Protein Size: 671 -
Gene ID
- 1436
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NCBI Accession
- NP_001275634
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UniProt
- E9PEK4
Target
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