Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (Middle Region) Peptide
CXCR1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512795
Quick Overview for Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (Middle Region) Peptide (ABIN5512795)
Target
CXCR1
(Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- ILLLACISVD RYLAIVHATR TLTQKRHLVK FVCLGCWGLS MNLSLPFFLF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CXCR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
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Background
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The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
Alias Symbols: C-C, CD128, CD181, CKR-1, IL8R1, IL8RA, CMKAR1, IL8RBA, CDw128a, C-C-CKR-1
Protein Size: 200 -
Gene ID
- 3577
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NCBI Accession
- NP_000625
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UniProt
- C9JW47
Target
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