Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (Middle Region) Peptide
CXCR1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CXCR1 products
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ILLLACISVD RYLAIVHATR TLTQKRHLVK FVCLGCWGLS MNLSLPFFLF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CXCR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
- Background
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The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
Alias Symbols: C-C, CD128, CD181, CKR-1, IL8R1, IL8RA, CMKAR1, IL8RBA, CDw128a, C-C-CKR-1
Protein Size: 200 - Gene ID
- 3577
- NCBI Accession
- NP_000625
- UniProt
- C9JW47
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