Bruton Agammaglobulinemia tyrosine Kinase (BTK) (N-Term) Peptide
BTK
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512832
Quick Overview for Bruton Agammaglobulinemia tyrosine Kinase (BTK) (N-Term) Peptide (ABIN5512832)
Target
BTK
(Bruton Agammaglobulinemia tyrosine Kinase (BTK))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- LTVHKLSYYE YDFERGRRGS KKGSIDVEKI TCVETVVPEK NPPPERQIPR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-BTK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
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Background
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The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: AT, ATK, BPK, XLA, IMD1, AGMX1, PSCTK1
Protein Size: 483 -
Gene ID
- 695
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NCBI Accession
- NM_000061, NP_000052
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UniProt
- Q5JY90
Target
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