Mitochondrial Calcium Uptake 1 (MICU1) (Middle Region) Peptide
MICU1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MICU1 products
- MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GMRHRDRPTT GNTLKSGLCS ALTTYFFGAD LKGKLTIKNF LEFQRKLQHD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CBARA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))
- Background
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This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: CALC, EFHA3, MPXPS, CBARA1
Protein Size: 278 - Gene ID
- 10367
- NCBI Accession
- NM_001195518, NP_001182447
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