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PTK2 Protein tyrosine Kinase 2 (PTK2) (Middle Region) Peptide

PTK2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5512999
  • Target See all FAK (PTK2) products
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 13
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    TILEEEKAQQ EERMRMESRR QATVSWDSGG SDEAPPKPSR PGYPSPRSSE
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- PTK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    Background
    This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined.

    Alias Symbols: FAK, FADK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK

    Protein Size: 1006
    Gene ID
    5747
    NCBI Accession
    NM_001199649, NP_001186578
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