PTK2 Protein tyrosine Kinase 2 (PTK2) (Middle Region) Peptide
PTK2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513000
Quick Overview for PTK2 Protein tyrosine Kinase 2 (PTK2) (Middle Region) Peptide (ABIN5513000)
Target
FAK (PTK2)
(PTK2 Protein tyrosine Kinase 2 (PTK2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- SWDSGGSDEA PPKPSRPGYP SPRSSEGFYP SPQHMVQTNH YQVSGYPGSH
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- PTK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
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Background
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This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined.
Alias Symbols: FAK, FADK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK
Protein Size: 1052 -
Gene ID
- 5747
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NCBI Accession
- NM_001199649, NP_001186578
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UniProt
- Q05397
Target
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