Glucokinase (Hexokinase 4) Regulator (GCKR) (N-Term) Peptide
GCKR
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513028
Quick Overview for Glucokinase (Hexokinase 4) Regulator (GCKR) (N-Term) Peptide (ABIN5513028)
Target
GCKR
(Glucokinase (Hexokinase 4) Regulator (GCKR))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- VIETPEPGKW ELSGYEAAVP ITEKSNPLTQ DLDKADAENI VRLLGQCDAE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GCKR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Glucokinase (Hexokinase 4) Regulator (GCKR) peptide
GCKR Reactivity: Human, Mouse, Rat Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
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Background
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This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Alias Symbols: GCKR,
Protein Size: 625 -
Gene ID
- 2646
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NCBI Accession
- NP_001477
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UniProt
- Q14397
Target
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