Kalirin, RhoGEF Kinase (KALRN) (Middle Region) Peptide
KALRN
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513045
Quick Overview for Kalirin, RhoGEF Kinase (KALRN) (Middle Region) Peptide (ABIN5513045)
Target
KALRN
(Kalirin, RhoGEF Kinase (KALRN))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- QGDSADEKSK KGWGEDEPDE ESHTPLPPPM KIFDNDPTQD EMSSLLAARQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-KALRN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KALRN (Kalirin, RhoGEF Kinase (KALRN))
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Background
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Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: DUO, CHD5, DUET, TRAD, CHDS5, HAPIP, ARHGEF24
Protein Size: 738 -
Gene ID
- 8997
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NCBI Accession
- NM_001024660, NP_001019831
Target
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