Kalirin, RhoGEF Kinase (KALRN) (Middle Region) Peptide
KALRN
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all KALRN products
- KALRN (Kalirin, RhoGEF Kinase (KALRN))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GRKSFDLGSP KPGDETTPQG DSADEKSKKG WGEDEPDEES HTPLPPPMKI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- KALRN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KALRN (Kalirin, RhoGEF Kinase (KALRN))
- Background
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Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: DUO, CHD5, DUET, TRAD, CHDS5, HAPIP, ARHGEF24
Protein Size: 738 - Gene ID
- 8997
- NCBI Accession
- NM_001024660, NP_001019831
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