High Mobility Group AT-Hook 1 (HMGA1) (N-Term) Peptide
HMGA1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513057
Quick Overview for High Mobility Group AT-Hook 1 (HMGA1) (N-Term) Peptide (ABIN5513057)
Target
HMGA1
(High Mobility Group AT-Hook 1 (HMGA1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- QPLASKQEKD GTEKRGRGRP RKQPPVSPGT ALVGSQKEPS EVPTPKRPRG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HMGA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
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Background
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This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: HMGA1,HMGIY,
Protein Size: 107 -
Gene ID
- 3159
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NCBI Accession
- XP_005249118
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UniProt
- P17096
Target
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