High Mobility Group AT-Hook 1 (HMGA1) (N-Term) Peptide
HMGA1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HMGA1 products
- HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MSESSSKSSQ PLASKQEKDG TEKRGRGRPR KQPPKEPSEV PTPKRPRGRP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HMGA1 Antibody(ARP38111_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
- Synonyms
- HMG-R Peptide, HMGA1A Peptide, HMGIY Peptide, Hmgi Peptide, Hmgiy Peptide, hmga1 Peptide, hmgiy Peptide, wu:fb12b06 Peptide, wu:fb18f11 Peptide, wu:fc19f01 Peptide, wu:fi38b05 Peptide, zgc:85677 Peptide, AL023995 Peptide, Hmga1a Peptide, Hmga1b Peptide, Hmgy Peptide, HMG-I(Y) Peptide, HMG-Y Peptide, HMGA1 Peptide, zgc:153948 Peptide, high mobility group AT-hook 1 Peptide, high mobility group protein HMG-I/HMG-Y Peptide, high mobility group AT-hook 1a Peptide, high mobility group AT-hook 1b Peptide, HMGA1 Peptide, Hmga1 Peptide, TSC_c24220 Peptide, hmga1a Peptide, LOC705105 Peptide, hmga1b Peptide
- Background
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This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: HMG-R, HMGA1A, HMGIY, MGC12816, MGC4242, MGC4854
Protein Interaction Partner: ATF2,CDK1,CEBPB,CREBBP,CSNK2A1,CSNK2A2,ELF1,EWSR1,HIPK2,IRF1,JUN,NFYA,POU3F1,PPARG,PRMT6,RARG,RNF4,RXRA,SP1,SRF,SUFU,ATF2,BANF1,CEBPB,CHD1,ELF1,EWSR1,INSR,IRF1,JUN,NFYA,NPM1,PARP1,POU3F1,PPARG,PRMT6,SP1
Protein Size: 96 - Molecular Weight
- 11 kDa
- Gene ID
- 3159
- NCBI Accession
- NM_002131, NP_002122
- UniProt
- Q5T6U8
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