Sad1 and UNC84 Domain Containing 2 (SUN2) (N-Term) Peptide
SUN2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513120
$160.46
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100 μg
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Quick Overview for Sad1 and UNC84 Domain Containing 2 (SUN2) (N-Term) Peptide (ABIN5513120)
Target
SUN2
(Sad1 and UNC84 Domain Containing 2 (SUN2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- RSQRLTRYSQ GDDDGSSSSG GSSVAGSQST LFKDSPLRTL KRKSSNMKRL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SUN2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))
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Background
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SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1, MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity.
Alias Symbols: SUN2,FRIGG,KIAA0668,RAB5IP,UNC84B,
Protein Size: 717 -
Gene ID
- 25777
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NCBI Accession
- XP_005261558
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UniProt
- Q9UH99
Target
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