Leupaxin (LPXN) (C-Term) Peptide
Quick Overview for Leupaxin (LPXN) (C-Term) Peptide (ABIN5513152)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- HGCGQPITGR CISAMGYKFH PEHFVCAFCL TQLSKGIFRE QNDKTYCQPC
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-LPXN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Leupaxin (LPXN)
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Background
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The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: LPXN,LDLP,
Protein Size: 386 -
Gene ID
- 9404
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NCBI Accession
- NP_004802
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UniProt
- O60711
Target
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