Regulator of G-Protein Signaling 1 (RGS1) (N-Term) Peptide
RGS1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513158
Quick Overview for Regulator of G-Protein Signaling 1 (RGS1) (N-Term) Peptide (ABIN5513158)
Target
RGS1
(Regulator of G-Protein Signaling 1 (RGS1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequence
- LKGTTHSLLD DKMQKRRPKT FGMDMKAYLR SMIPHLESGM KSSKSKDVLS
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-RGS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- RGS1 (Regulator of G-Protein Signaling 1 (RGS1))
-
Background
-
This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Alias Symbols: RGS1,1R20,BL34,IER1,
Protein Size: 209 -
Gene ID
- 5996
-
NCBI Accession
- NP_002913
-
UniProt
- Q08116
Target
-
You are here:
