Glycine Dehydrogenase (GLDC) (N-Term) Peptide
GLDC
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513169
$160.46
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100 μg
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Quick Overview for Glycine Dehydrogenase (GLDC) (N-Term) Peptide (ABIN5513169)
Target
GLDC
(Glycine Dehydrogenase (GLDC))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- LAGGSGPCWA PRSRDSSSGG GDSAAAGASR LLERLLPRHD DFARRHIGPG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- GLDC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GLDC (Glycine Dehydrogenase (GLDC))
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Background
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Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
Alias Symbols: GCE, GCSP, HYGN1
Protein Size: 1020 -
Gene ID
- 2731
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NCBI Accession
- NM_000170, NP_000161
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UniProt
- P23378
Target
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