Glucuronic Acid Epimerase (GLCE) (Middle Region) Peptide
GLCE
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513184
$160.46
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100 μg
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Quick Overview for Glucuronic Acid Epimerase (GLCE) (Middle Region) Peptide (ABIN5513184)
Target
GLCE
(Glucuronic Acid Epimerase (GLCE))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- TKDHIFLNSA LRATAPYKFL SEQHGVKAVF MNKHDWYEEY PTTPSSFVLN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GLCE Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GLCE (Glucuronic Acid Epimerase (GLCE))
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Background
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Heparan sulfate (HS) is a negatively charged cell surface polysaccharide required for the biologic activities of circulating extracellular ligands. GLCE is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) of HS, which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines (Ghiselli and Agrawal, 2005 [PubMed 15853773]).[supplied by OMIM, Jun 2008]
Alias Symbols: HSEPI
Protein Size: 617 -
Gene ID
- 26035
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NCBI Accession
- NM_015554, NP_056369
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UniProt
- O94923
Target
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