H2A Histone Family, Member Z (H2AFZ) (N-Term) Peptide
H2AFZ
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513193
$160.46
Plus shipping costs $50.00
100 μg
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Quick Overview for H2A Histone Family, Member Z (H2AFZ) (N-Term) Peptide (ABIN5513193)
Target
H2AFZ
(H2A Histone Family, Member Z (H2AFZ))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- GKAGKDSGKA KTKAVSRSQR AGLQFPVGRI HRHLKSRTTS HGRVGATAAV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-H2AZ Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- H2AFZ (H2A Histone Family, Member Z (H2AFZ))
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Background
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
Alias Symbols: H2AFZ,H2AZ,
Protein Size: 128 -
Gene ID
- 3015
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NCBI Accession
- NP_002097
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UniProt
- P0C0S5
Target
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