Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) (Middle Region) Peptide
FGFRL1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513194
$160.46
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100 μg
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Quick Overview for Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) (Middle Region) Peptide (ABIN5513194)
Target
FGFRL1
(Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- RPDITWMKDD QALTRPEAAE PRKKKWTLSL KNLRPEDSGK YTCRVSNRAG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-FGFRL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
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Background
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The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Alias Symbols: FGFRL1,FGFR5,FHFR,UNQ480/PRO943,
Protein Size: 504 -
Gene ID
- 53834
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NCBI Accession
- XP_005272339
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UniProt
- Q8N441
Target
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