conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (Middle Region) Peptide
CHUK
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513207
Quick Overview for conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (Middle Region) Peptide (ABIN5513207)
Target
IKK alpha (CHUK)
(conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- GRRQGDLMES LEQRAIDLYK QLKHRPSDHS YSDSTEMVKI IVHTVQSQDR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- CHUK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
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Background
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This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Alias Symbols: IKK1, IKKA, IKBKA, TCF16, NFKBIKA, IKK-alpha
Protein Size: 745 -
Gene ID
- 1147
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NCBI Accession
- NM_001278, NP_001269
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UniProt
- O15111
Target
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