EPH Receptor B2 (EPHB2) (C-Term) Peptide
EPHB2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513369
Quick Overview for EPH Receptor B2 (EPHB2) (C-Term) Peptide (ABIN5513369)
Target
EPH Receptor B2 (EPHB2)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- PRATGRTKRC QPRDVTKKTC NSNDGKKKGM GKKKTDPGRG REIQGIFFKE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-EPHB2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EPH Receptor B2 (EPHB2)
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Background
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This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.
Alias Symbols: DRT, EK5, ERK, CAPB, Hek5, PCBC, EPHT3, Tyro5
Protein Size: 1055 -
Gene ID
- 2048
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NCBI Accession
- NM_001309193, NP_004433
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UniProt
- P29323
Target
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