Lysine (K)-Specific Demethylase 4B (KDM4B) (N-Term) Peptide
KDM4B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all KDM4B products
- KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- IPPKEWKPRQ TYDDIDDVVI PAPIQQVVTG QSGLFTQYNI QKKAMTVGEY
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KDM4B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))
- Background
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KDM4B is a histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. It does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Alias Symbols: KDM4B,JHDM3B, JMJD2B, KIAA0876,
Protein Size: 1096 - Gene ID
- 23030
- NCBI Accession
- NP_055830
- UniProt
- O94953
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