Lysine (K)-Specific Demethylase 4B (KDM4B) (N-Term) Peptide
KDM4B
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513396
Quick Overview for Lysine (K)-Specific Demethylase 4B (KDM4B) (N-Term) Peptide (ABIN5513396)
Target
KDM4B
(Lysine (K)-Specific Demethylase 4B (KDM4B))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- IPPKEWKPRQ TYDDIDDVVI PAPIQQVVTG QSGLFTQYNI QKKAMTVGEY
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-KDM4B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))
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Background
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KDM4B is a histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. It does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Alias Symbols: KDM4B,JHDM3B, JMJD2B, KIAA0876,
Protein Size: 1096 -
Gene ID
- 23030
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NCBI Accession
- NP_055830
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UniProt
- O94953
Target
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