Megakaryocyte-Associated tyrosine Kinase (MATK) (C-Term) Peptide
MATK
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513404
$160.46
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100 μg
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Quick Overview for Megakaryocyte-Associated tyrosine Kinase (MATK) (C-Term) Peptide (ABIN5513404)
Target
MATK
(Megakaryocyte-Associated tyrosine Kinase (MATK))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- SSCWEAEPAR RPPFRKLAEK LARELRSAGA PASVSGQDAD GSTSPRSQEP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MATK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))
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Background
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The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.
Alias Symbols: MATK, CTK, HYL,
Protein Size: 507 -
Gene ID
- 4145
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NCBI Accession
- NP_647612
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UniProt
- P42679
Target
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