NOP2/Sun Domain Family, Member 2 (NSUN2) (N-Term) Peptide
NSUN2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513462
Quick Overview for NOP2/Sun Domain Family, Member 2 (NSUN2) (N-Term) Peptide (ABIN5513462)
Target
NSUN2
(NOP2/Sun Domain Family, Member 2 (NSUN2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- LEKFHQFLVS ETESGNISRQ EAVSMIPPLL LNVRPHHKIL DMCAAPGSKT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NSUN2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
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Background
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NSUN2 is a RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. NSUN2 methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. It may act downstream of Myc to regulate epidermal cell growth and proliferation. And it is required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.
Alias Symbols: NSUN2,SAKI, TRM4,
Protein Size: 767 -
Gene ID
- 54888
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NCBI Accession
- NP_060225
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UniProt
- Q08J23
Target
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