PML-RARA Regulated Adaptor Molecule 1 (PRAM1) (Middle Region) Peptide
PRAM1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513507
Quick Overview for PML-RARA Regulated Adaptor Molecule 1 (PRAM1) (Middle Region) Peptide (ABIN5513507)
Target
PRAM1
(PML-RARA Regulated Adaptor Molecule 1 (PRAM1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Sequence
- HFQDRQPEDI PQVPDEIYEL YDDVEPRDDS SPSPKGRDEA PSVQQAARRP
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti- PRAM1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))
-
Background
-
The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).
Alias Symbols: PRAM-1, PML-RAR
Protein Size: 718 -
Gene ID
- 84106
-
NCBI Accession
- NM_032152, NP_115528
-
UniProt
- Q96QH2
Target
-
You are here:
