phosphodiesterase 11A (PDE11A) (N-Term) Peptide
PDE11A
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513530
Quick Overview for phosphodiesterase 11A (PDE11A) (N-Term) Peptide (ABIN5513530)
Target
PDE11A
(phosphodiesterase 11A (PDE11A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequence
- WAGGSRGDGN LQRRASQKEL RKSFARSKAI HVNRTYDEQV TSRAQEPLSS
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-PDE11A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- PDE11A (phosphodiesterase 11A (PDE11A))
-
Background
-
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PPNAD2
Protein Size: 933 -
Gene ID
- 50940
-
NCBI Accession
- NM_001077196, NP_001070664
-
UniProt
- Q9HCR9
Target
-
You are here:
