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phosphodiesterase 11A (PDE11A) (N-Term) Peptide

PDE11A Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5513530
  • Target See all PDE11A products
    PDE11A (phosphodiesterase 11A (PDE11A))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 11
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    WAGGSRGDGN LQRRASQKEL RKSFARSKAI HVNRTYDEQV TSRAQEPLSS
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PDE11A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PDE11A (phosphodiesterase 11A (PDE11A))
    Background
    The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: PPNAD2

    Protein Size: 933
    Gene ID
    50940
    NCBI Accession
    NM_001077196, NP_001070664
    UniProt
    Q9HCR9
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