UDP Glucuronosyltransferase 1 Family, Polypeptide A5 (UGT1A5) (Middle Region) Peptide
UGT1A5
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513683
Quick Overview for UDP Glucuronosyltransferase 1 Family, Polypeptide A5 (UGT1A5) (Middle Region) Peptide (ABIN5513683)
Target
UGT1A5
(UDP Glucuronosyltransferase 1 Family, Polypeptide A5 (UGT1A5))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- QDEFDRLLLG HTQSFFETEH LLMKFSRRMA IMNNMSLIIH RSCVELLHNE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-UGT1A5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UGT1A5 (UDP Glucuronosyltransferase 1 Family, Polypeptide A5 (UGT1A5))
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Background
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This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter.
Alias Symbols: UDPGT, UGT1E, UDPGT 1-5
Protein Size: 534 -
Gene ID
- 54579
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NCBI Accession
- NM_019078, NP_061951
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UniProt
- P35504
Target
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