REV1, Polymerase (DNA Directed) (REV1) (C-Term) Peptide
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- Target See all REV1 products
- REV1 (REV1, Polymerase (DNA Directed) (REV1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- INLIALPAFS QVDPEVFAAL PAELQRELKA AYDQRQRQGE NSTHQQSASA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-REV1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- REV1 (REV1, Polymerase (DNA Directed) (REV1))
- Background
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This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found.
Alias Symbols: REV1, REV1L,
Protein Size: 1251 - Gene ID
- 51455
- NCBI Accession
- XP_005264024
- UniProt
- Q9UBZ9
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