MNT, MAX Dimerization Protein (MNT) (C-Term) Peptide
Quick Overview for MNT, MAX Dimerization Protein (MNT) (C-Term) Peptide (ABIN5514176)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- AAPAQTLVPA PAHLVATAGG GSTVIAHTAT THASVIQTVN HVLQGPGGKH
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MNT Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MNT (MNT, MAX Dimerization Protein (MNT))
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Background
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The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.
Alias Symbols: MNT,BHLHD3,ROX,
Protein Size: 582 -
Gene ID
- 4335
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NCBI Accession
- NP_064706
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UniProt
- Q99583
Target
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