MNT, MAX Dimerization Protein (MNT) (C-Term) Peptide
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- Target See all MNT products
- MNT (MNT, MAX Dimerization Protein (MNT))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AAPAQTLVPA PAHLVATAGG GSTVIAHTAT THASVIQTVN HVLQGPGGKH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MNT Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MNT (MNT, MAX Dimerization Protein (MNT))
- Background
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The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.
Alias Symbols: MNT,BHLHD3,ROX,
Protein Size: 582 - Gene ID
- 4335
- NCBI Accession
- NP_064706
- UniProt
- Q99583
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