Aldehyde Dehydrogenase 7 Family, Member A1 (ALDH7A1) (C-Term) Peptide
ALDH7A1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5514366
$160.46
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100 μg
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Quick Overview for Aldehyde Dehydrogenase 7 Family, Member A1 (ALDH7A1) (C-Term) Peptide (ABIN5514366)
Target
ALDH7A1
(Aldehyde Dehydrogenase 7 Family, Member A1 (ALDH7A1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LGRIFRWLGP KGSDCGIVNV NIPTSGAEIG GAFGGEKHTG GGRESGSDAW
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- ALDH7A1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ALDH7A1 (Aldehyde Dehydrogenase 7 Family, Member A1 (ALDH7A1))
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Background
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The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.
Alias Symbols: EPD, PDE, ATQ1
Protein Size: 475 -
Gene ID
- 501
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NCBI Accession
- NM_001182, NP_001173
Target
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