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6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (C-Term) Peptide

PFKFB2 Reactivity: Human Host: Synthetic WB
Catalog No. ABIN5518158
  • Target See all PFKFB2 products
    PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 8
    Synthetic
    Application
    Western Blotting (WB)
    Sequence
    YLRCPLHTIF KLTPVAYGCK VETIKLNVEA VNTHRDKPTN NFPKNQTPVR
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))
    Synonyms
    pfkfb2 Peptide, zgc:56282 Peptide, PFK-2/FBPase-2 Peptide, 4930568D07Rik Peptide, RH2K Peptide, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a Peptide, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 Peptide, pfkfb2a Peptide, PFKFB2 Peptide, pfkfb2 Peptide, Pfkfb2 Peptide
    Background
    The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.

    Alias Symbols: PFK-2/FBPase-2

    Protein Size: 167
    Gene ID
    5208
    NCBI Accession
    NM_001018053, NP_001018063
    UniProt
    O60825
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