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Transducin (Beta)-Like 1X-Linked (TBL1X) (Middle Region) Peptide

TBL1X Reactivity: Human Host: Synthetic WB
Catalog No. ABIN5518219

Quick Overview for Transducin (Beta)-Like 1X-Linked (TBL1X) (Middle Region) Peptide (ABIN5518219)

Target

TBL1X (Transducin (Beta)-Like 1X-Linked (TBL1X))

Origin

Human

Source

  • 3
Synthetic

Application

Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequence

    HNKEIYTIKW SPTGPATSNP NSNIMLASAS FDSTVRLWDI ERGVCTHTLT
  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    TBL1X (Transducin (Beta)-Like 1X-Linked (TBL1X))

    Background

    The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.

    Alias Symbols: EBI, TBL1, SMAP55

    Protein Size: 167

    Gene ID

    6907

    NCBI Accession

    NM_001139466, NP_001132938

    UniProt

    O60907
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