Transducin (Beta)-Like 1X-Linked (TBL1X) (Middle Region) Peptide
Quick Overview for Transducin (Beta)-Like 1X-Linked (TBL1X) (Middle Region) Peptide (ABIN5518219)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- HNKEIYTIKW SPTGPATSNP NSNIMLASAS FDSTVRLWDI ERGVCTHTLT
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TBL1X (Transducin (Beta)-Like 1X-Linked (TBL1X))
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Background
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The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
Alias Symbols: EBI, TBL1, SMAP55
Protein Size: 167 -
Gene ID
- 6907
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NCBI Accession
- NM_001139466, NP_001132938
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UniProt
- O60907
Target
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